Cardiovascular disease is still the top cause of mortality worldwide and cognitive decline is a close second, as a key worry for ageing populations. Both diseases have an unexpected commonality: chronic inflammation, oxidative stress, and a prolonged deficiency of marine omega-3 fatty acids. It’s the same common biology that has made krill oil with highest astaxanthin one of the most exciting substances in heart and brain nourishment. The same softgel provides a mix of phospholipid-bound EPA and DHA with naturally occurring astaxanthin that acts on both systems. In this article, we take a look at the mechanics, the clinical data, the dosage techniques and the sourcing options that brand owners need to understand to design a viable heart-and-brain product. NT Biotech produces high astaxanthin krill oil, ISO 9001, Kosher and Halal certified, CoA on every batch, free samples, in-stock inventory. For a custom specification please contact us at info@newthingsbiotech.com.

Before we get directly into krill oil, it helps to understand why these two systems react so effectively to the same dietary intervention.
The arteries that feed the heart and the microvessels that feed the brain have more in common than their layout. Both are subject to the same chronic processes: oxidised LDL cholesterol, endothelial dysfunction, low-grade systemic inflammation and mitochondrial fatigue. Any vitamin that decreases oxidative stress and inflammation is probably healthy for both organs. And this is exactly why population studies have consistently shown that communities with diets rich in marine omega-3s and carotenoids had consistently lower rates of both cardiovascular events and age-related cognitive decline.
EPA and DHA are the most appropriate dietary lipids for this dual function. EPA competes with arachidonic acid within inflammatory pathways, decreasing production of pro-inflammatory eicosanoids. DHA is the most abundant fatty acid in the membranes of brain cells where it helps to maintain fluidity, synaptic function and signal transmission. They are the two most studied marine lipids in cardiology and neurology.
Astaxanthin from krill oil adds a third dimension to it. Astaxanthin is one of the few antioxidants that can cross the blood brain barrier and the blood retina barrier. This also prevents the EPA and DHA in the softgel from oxidising. For a buyer it means fresher raw material upon opening and a greater functional story on the label.

The most studied area of krill oil is cardiovascular health. This is how the science turns into product promises.
A landmark trial in nutrition 2014 Research has shown that krill oil was successful in decreasing blood triglycerides in patients with borderline high to high blood levels without raising LDL cholesterol levels. Another study from 2017, published in Lipids in Health and Disease, similarly found that krill oil marginally increased HDL cholesterol levels — the “good” cholesterol that’s associated to a lower risk of heart disease. This research basis for brand teams enables credible heart-health positioning beyond generic omega-3 claims.
The endothelium, the lining of the blood vessels, determines how arteries expand and respond to stress. Oxidative damage to this layer is among the initial events in cardiovascular disease. Natural astaxanthin krill oil seems to promote endothelial function via two complimentary mechanisms: EPA increases nitric oxide signalling and astaxanthin scavenges reactive oxygen species that would otherwise damage the vessel wall. Clinical trials using marine omega-3s + astaxanthin have shown moderate but lasting benefits in flow mediated dilation and blood pressure markers in adults.
| Heart-Health Specification | Suggested Benchmark |
|---|---|
| Astaxanthin (esters) | ≥300 ppm (premium) or ≥800 ppm (super high) |
| Total phospholipids (³¹P-NMR) | ≥48% |
| EPA + DHA | ≥24% |
| Choline | ≥60 mg/g |
| Peroxide value | ≤3 meq/kg |
| Anisidine value | ≤20 |
| Certifications | ISO 9001, Kosher, Halal; MSC traceable |
The brain-health narrative for krill oil is younger than the heart tale, but it’s coming up fast. Here’s what the present evidence supports:
DHA makes up around 97 percent of all the omega-3 fats in the brain. The DHA in krill oil is bound to phosphatidylcholine, which is the major phospholipid in neuronal membranes. Perhaps this structural similarity is why some studies indicates that phospholipid-bound DHA is incorporated into brain tissue more effectively than triglyceride-bound DHA . In a 2013 randomised controlled experiment published in Clinical Interventions in Ageing, researchers found that healthy older persons who took phospholipid-bound krill oil saw substantial increases in cognitive performance scores over a 12-week period.
Few antioxidants penetrate the brain in significant amounts. The only exception is astaxanthin. Astaxanthin has been demonstrated to pass the blood-brain barrier and accumulate in neural tissue, protecting mitochondria and reducing oxidative stress in research published in Marine Drugs and Nutrients . Clinical research have shown that the supplementation of astaxanthin is associated with improvements in response speed, working memory and multitasking performance in middle-aged persons with age-related cognitive problems.
In addition to typical cognitive ageing, krill oil containing astaxanthin has attracted attention in mood and everyday mental function. DHA and phosphatidylcholine (a direct precursor to the neurotransmitter acetylcholine) and astaxanthin work together to target numerous of the pathways that enhance attention, mental energy and emotional equilibrium. Need assistance developing a concentration or memory softgel? Please send your target audience and softgel size to info@newthingsbiotech.com. Our technical staff will get back to you within two hours with a suggested specification and arrange free samples to start bench work immediately.

First step, you need know the mechanics. Next you need to convert it into a complete SKU that your QC team, your marketing team and your customer can all get behind
Standard krill oil with astaxanthin at 100–200 ppm, >40% phospholipids and >22% EPA + DHA is an inexpensive and reliable option for everyday general wellbeing. Premium heart-brain combos for an educated adult audience may command a higher price point with ultra high-astaxanthin krill oil (800-1500 ppm) that provides a stand alone antioxidant claim without a second ingredient line.
Krill oil astaxanthin complements CoQ10 for heart-energy formulations, and phosphatidylserine, bacopa or B-complex vitamins for cognitive support. If you’re an older adult, a combination of vitamin D3 and vitamin K2 hits both your cardiovascular and bone health in a single daily dose. Do not combine with highly reactive iron sources in the same softgel as this may increase omega-3 oxidation.
The table below summarises typical doses used in clinical research and premium commercial formulations.
| Target Benefit | Daily Krill Oil Dose | Best Grade |
|---|---|---|
| Daily heart maintenance | 500–1,000 mg | Standard (100–200 ppm) |
| Elevated triglyceride support | 1,000–2,000 mg | Premium (300–500 ppm) |
| Cognitive wellness, 50+ | 1,000–2,000 mg | Premium (300–500 ppm) |
| Mental energy and focus | 500–1,000 mg | Super high (800–1,500 ppm) |
| Combined heart-brain premium SKU | 1,000 mg | Super high (800–1,500 ppm) |
Krill oil is available in soft gelatin or vegetarian plant-based capsules. Minimise oxygen headspace. Use amber or metallized blister packing for light protection. Specify tocopherols or rosemary extract in the fill to increase oxidative stability.

A fantastic standard is only as good as the raw material behind it – consistent, pure and sustainable. The last element of the jigsaw is selecting the proper krill oil with the highest astaxanthin provider.
Ask where the krill is fished, whether the fishery is MSC-certified and how fast the oil is collected after capture. Shorter catch-extraction windows sustain native astaxanthin levels and minimal oxidation indicators. NT Biotech’s krill oil program is intended to ensure freshness from the Antarctic fishery to your storage.
All NT Biotech lots are sent with a CoA that includes astaxanthin, phospholipids, EPA, DHA, oxidation indicators, heavy metals and microbiological. ISO 9001, Kosher and Halal certifications assist with export paperwork and rigorous retail audits. This converts incoming inspection into a fast confirmation and not a day long investigation for QC personnel.
| Service Area | NT Biotech Commitment |
|---|---|
| Inquiry response | First reply within 2 hours |
| In-stock grades | Shipment in 1–3 working days after order confirmation |
| Production orders | 3–10 working days, from sourcing to packing |
| Shipping options | Express via FedEx/UPS, air or sea through trusted forwarders |
| Customization | OEM/ODM astaxanthin levels, encapsulation and private-label packing |
| Payment | Flexible options, including the buyer's local currency |
Shaanxi New Things Biotech is more than a delivery. With its own sourcing network, R&D, and intelligent manufacturing, Shaanxi New Things Biotech has become a long-term technical partner of heart-brain health companies, instead of an ingredient vendor.

The enemies of a healthy heart and brain are the same – oxidation and chronic inflammation – and so are their allies, EPA, DHA and natural antioxidants. The krill oil with highest astaxanthin provides all three in one softgel, with phospholipid delivery that benefits both the arteries and the neurones. The evidence is greatest for lipid lowering, endothelial and cognitive health in ageing individuals, with emerging evidence for mental vigour and attention. Shaanxi New Things Biotech is a technology-based ingredient firm offering several standardised grades, ISO 9001, Kosher and Halal certification, CoA on every batch and delivery in days. Order your free sample now and develop a foundation your consumers can depend on for your future heart-brain softgel.
A: Both systems share inflammation and oxidative stress pathways, so marine omega-3s plus astaxanthin benefit them together.
A: Super high-astaxanthin krill oil at 800–1,500 ppm with ≥48% phospholipids.
A: Research suggests phospholipid-bound EPA and DHA achieve similar blood levels at lower doses than triglyceride fish oil.
A: ISO 9001, Kosher and Halal, with a CoA for every batch.
A: In-stock grades ship in 1–3 working days. Production orders take 3–10 working days.
“The fastest-growing segment of global supplements are consumers over 40 years old and heart-brain combinations are right in the thick of it.” NT Biotech is here to help you get started. Our krill oil with highest astaxanthin on the market, available in standard, premium and super-high-astaxanthin grades, is ISO 9001, Kosher and Halal certified and comes with a complete CoA for every batch and a two-hour response assurance. Whether you’re developing a daily cardiac softgel, a cognitive wellness capsule for senior individuals, a focus-and-energy product for busy professionals, or a combined heart-brain premium SKU, our staff can assist you in selecting the proper specification and planning shipment by express, air or sea. Local currency payments and flexible OEM choices making every project straightforward. Contact info@newthingsbiotech.com immediately for free samples, a technical data sheet and a bulk quote.
1. Berge, K., Musa-Veloso, K., Harwood, M., Hoem, N., & Burri, L. (2014). Krill oil supplementation lowers serum triglycerides without increasing low-density lipoprotein cholesterol in adults with borderline high or high triglyceride levels. Nutrition Research, 34(2), 126–133.
2. Konagai, C., Yanagimoto, K., Hayamizu, K., Han, L., Tsuji, T., & Koga, Y. (2013). Effects of krill oil containing n-3 polyunsaturated fatty acids in phospholipid form on human brain function: A randomized controlled trial in healthy elderly volunteers. Clinical Interventions in Aging, 8, 1247–1257.
3. Ulven, S. M., Kirkhus, B., Lamglait, A., Basu, S., Elind, E., Haider, T., Berge, K., Vik, H., & Pedersen, J. I. (2011). Metabolic effects of krill oil are essentially similar to those of fish oil but at lower dose of EPA and DHA, in healthy volunteers. Lipids, 46(1), 37–46.
4. Katagiri, M., Satoh, A., Tsuji, S., & Shirasawa, T. (2012). Effects of astaxanthin-rich Haematococcus pluvialis extract on cognitive function: A randomised, double-blind, placebo-controlled study. Journal of Clinical Biochemistry and Nutrition, 51(2), 102–107.
5. Fakhri, S., Abbaszadeh, F., Dargahi, L., & Jorjani, M. (2018). Astaxanthin: A mechanistic review on its biological activities and health benefits. Pharmacological Research, 136, 1–20.
6. Grimstad, T., Berge, R. K., Bohov, P., Skorve, J., Gøransson, L., Omdal, R., Aasprong, O. G., Haugen, M., Meltzer, H. M., & Hausken, T. (2012). Salmon diet in patients with active ulcerative colitis reduced the simple clinical colitis activity index and increased the anti-inflammatory fatty acid index — a pilot study. Scandinavian Journal of Gastroenterology, 47(2), 102–111.